Patient recruitment is one of the biggest bottlenecks in clinical research. Failure to meet enrollment targets creates costly delays, and more importantly, impacts the time that it takes to bring new medicines into the hands of patients that need them. The Enrollment Planning and Patient Recruitment track highlights strategies to enroll for global trials, leverage data analytics to improve recruitment, retention and diversity, and tactics to improve up-front enrollment planning. The Patient Engagement and Retention through Communities and Technology track explores pathways to engage diverse populations, how to leverage technology without losing sight of the participant’s user experience and potential technology burden, and strategies to support sites given ongoing resource constraints.